A new sequencing technology enters the ring: SHTseq(TM)

Just received this press release from Neil Hall, CEO of a new sequencing company called CrapBio who's launching at this year's #notAGBT.. sounds very interesting!

CrapBio is excited to announce the release of its new SHTseq™ whole genome sequencing platform which is going to revolutionize the genomics industry and soon the healthcare industry.

SHTseq or Super High-throughput Template sequencing is a totally new paradigm for DNA analysis. In the era of second and third generation sequencing, scientists would take days to extract DNA and prepare it for analysis on slow cumbersome analysis machines. CrapBio is able to get around this using AngstromRealtimeSensors™ that can accurately read the DNA while still inside cells. Better than that, you don’t even need to take the DNA to the analysis machine you can simply take an image of the organism you wish to sequence and upload it to the SHTcloud and have the DNA information extracted directly by out highly trained SHTtechnicians.

With SHTseq you can simply send the sample from you iphone and have the sequencing data returned to your email address in a matter of minutes. THATS RIGHT!, you can have a SHT experiment run in minutes! Not hours or days. Download your iSHT app now and start sequencing.

Longer Reads-Better Data – noSHT (What would you do with 100Mb reads?).
We are able to generate super-long reads with our ARSesnsors. Using CrapBio-SHTseq technology we regularly get 10Mb reads and we have even seen reads of 100Mb which completely sequenced E. coli 20 times in a single read. Our base calling accuracy is 25%, but with genomes with extreme AT/GC bias it reaches 40%. Although this is lower than other platforms the longer reads allow you to extract much more information from our reads than old-fashioned 2nd generation sequencers. Also this error is totally randomly distributed (unlike homopolymer errors in other technologies!) and there is no decline in base calling accuracy toward the ends of reads. The last base in a read is just as good as the first base.

Cleaning up SHT™ with Illumina data
If, for whatever reason, you need accurate sequence data we have developed hybrid assembler that can incorporate Illumina error correcting reads. With our HybridAssemblyReadDenoisingSHT data you can simply upload you 100x illumina data with your sample and get reads returned to you will 99.999% accuracy*

CompleteSHT™ our human genome analysis service
Finally we are pleased to announce our CompleteSHT human genome sequencing service. We have optimized our laboratory and informatics pipelines for human DNA sequencing and are able generate a DNA sequence de novo, without HARDSHT, with 99.9% accuracy**. Simply send the name, ethnicity and starsign of the subject and we can return a SNP file to your email address INSTENTAINIOUSLY!***.

How much does SHT cost?
Due to the way our technology works we have very low reagent costs, therefore SHTseq is the cheapest technology on the market. Speak to a CrapBio representative to find out more.

More SHT
If you would like to speak to one of our product specialists to find out how SHT will change the way you do science please email SHT@CRP.COM

*there may be a high chimera rate with this product.
** this works best with samples of European decent
*** for research use only